Diana Silva, PhD student from the Structural Biology and Drug Discovery group at iBET received the “Best Poster Prize” awarded at the 7th International School on Biological Crystallization, held from the 26th to the 31st of May 2019, in Granada, Spain.
The awarded poster presentation described part of Diana’s PhD work on Cyclophilin D – a protein with a fundamental role in mitochondrial regulation. Mitochondrial dysfunction has been implicated in several neurological and cardiovascular diseases thus making Cyclophilin D a very interesting drug target. The awarded work represents a step forward into the discovery of new inhibitors of Cyclophilin D through the use of fragment-based drug discovery approach.
The International School on Biological Crystallization focused the fundamentals of crystallization of biological macromolecules. ISBC2019 provides an immersive experience with five days of lectures and practical demonstrations related to the crystallization of biological macromolecules, biominerals and biomimetic materials, with one full day devoted to case studies on the crystallization of membrane proteins, viruses and large macromolecular complexes.
